Best Commercial Weight Loss Programs Pair Diet with Exercise Greatest improvement in metabolic syndrome (MetS) was seen in women involved in commercial weight loss programs that incorporated both diet and exercise, results of a small prospective trial indicated. The randomized, controlled, 12-week trial of 133 overweight and obese women found that those who completed the Curves Complete 90-Day Challenge had the greatest reduction in MetS prevalence (35% versus 14%) when compared to other commercial weight loss programs, according to Claire Baetge, PhD, of the University of Texas San Antonio, and colleagues.
A commercial weight loss program that incorporated exercise led to greater improvements in features of metabolic syndrome (MetS) compared to weight loss programs that did not incorporate specific exercise requirements.
Note that the study, which lasted only 12 weeks, randomized only 133 overweight and obese women to 4 weight loss programs, only one of which mandated exercise, and a control group. Published online in Applied Physiology, Nutrition, and Metabolism, the researchers assigned participants to the Curves program -- a combined diet and exercise regimen -- or to one of three diet-based programs that advocate increased physical activity but with no specific requirement (Weight Watchers Points Plus, Jenny Craig At Home, Nutrisystem Advance Select). The study also included a wait-listed control group who were instructed not to change their diet and exercise habits for 12 weeks, after which they were given one of the four interventions.
"For many decades, despite the advocacy of nutrition and exercise as a means to improve health, lose and/or maintain weight, there seems to be an emphasis on either one or the other," co-author Conrad Earnest, PhD, of Texas A&M University in College Station, said to MedPage Today. "This holds true for commercial programs offering diet programs advocating exercise. Yet, the underlying assumption is that people will exercise or engage in physical activity on their own. Few do. Given the American College of Sports Medicine's continued advocacy for 'Exercise is Medicine,' we decided to examine several commercial programs, only one of which provided a direct avenue for exercise."
Compared to the control, participants across all intervention groups experienced significant trends for reductions for the prevalence of metabolic syndrome (P for trend=0.006), reduction in body mass (all P <0.001), reduction in waist circumference (all P < 0.003), and drop in percentage of body fat (all P <0.02). Absolute maximal cardiorespiratory fitness level improved the most among the Curves Complete group after 12 weeks (0.11 L/min; 95% CI 0.05-0.17).
Earnest said the team was not surprised by the results. "While negative caloric balance, regardless of means, will aid weight loss, the benefits associated from physical activity have benefits related to the act of physical exertion that are not mirrored by diet alone." The Weight Watchers program included a diet regimen, which involved a point system for measuring food intake. Weekly meetings were mandatory for the participants, while physical activity was encouraged, but not mandatory. The Jenny Craig program involved an online diet program, with meals provided. A goal of 30-minutes of moderate exercise over five or more day per week was highly encouraged for participants. The Nutrisystem program included a diet plan of prepared fresh or frozen meals, centered on the Glycemic Index. Exercise was encouraged, but not mandatory. The Curves program included a diet regimen, involving caloric-intake measurement and guidance from the company's diet book, and exercise was mandatory with supervised, 30-minute training sessions four times per week. (Curves International funded the study.)
All participants were tested at baseline and during three follow-up periods throughout the study, to measure for resting energy expenditure and cardiorespiratory fitness. Blood samples were collected to measure cholesterol, insulin levels, and other variables. Weekly physical activity logs, as well as dietary history were self-reported.
While all commercial weight loss programs evaluated in the study did yield significant weight loss for participants, the authors noted the Curves program, followed by Weight Watchers, were most effective at MetS risk reduction. Baetge and colleagues also noted that lean body mass was only maintained by the Curves program group, while the Jenny Craig and Nutrisystem participants actually showed slightly increased triglyceride levels by the end of 12 weeks. Similarly, the Jenny Craig group experienced a significant drop in protein consumption, below the recommended daily intake guidelines for sedentary individuals, yet maintained within the guidelines for physically active individuals. Although the trial was keen to conduct analysis of several health outcomes, limits included a restriction of results to only the programs analyzed in the study, as well as small sample size across intervention groups.
Earnest told MedPage Today that combined diet-and-exercise programs are scarce and, while future research would be valuable, it's unclear whether funding will be forthcoming. "These studies cost a lot of money and I don't see commercial diet programs anteing up research funds to examine their programs in combination with exercise. I am, however, open to being surprised and am certainly willing to help them out should they desire to do so."
The American Association of Clinical Endocrinologist’s 2016 guidelines for medical care of patients with obesity can be found here.
Curves International provided funding for this research. Earnest is a paid consultant for Naturally Slim and Catapult Health. No other relevant conflicts of interest were declared. Reviewed by Henry A. Solomon, MD, FACP, FACCClinical Associate Professor, Weill Cornell Medical College and Dorothy Caputo, MA, BSN, RN, Nurse Planner
Applied Physiology, Nutrition, and Metabolism
Source Reference: Baetge C, et al "Efficacy of a randomized trail examining commercial weight loss programs and exercise on metabolic syndrome in overweight and obese women" Applied Physiology, Nutrition, and Metabolism 2017; DOI: 10.1139/apnm-2016-0456.